Study: Positive Effects of Soy Lecithin on Fatigue in Menopausal Women

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By Menopause Now Editorial Team | Updated: Jan 02, 2022


Dealing with fatigue can make menopausal women feel miserable, unable to carry on with their daily duties and enjoy life. While soy is popularly used for menopause symptoms, soy lecithin (a mixture of phospholipids) has not been previously studied for fatigue relief. As such, a Japanese trial investigated the effects of soy lecithin on fatigue in middle-aged women.

Study: Positive effects of soy lecithin on fatigue in menopausal women

Study Design

This study was conducted by researchers from Tokyo Medical and Dental University in Japan, who published their findings in the Nutrition Journal.

To put their hypothesis to the test, they recruited 96 women between the ages of 40 and 60 who reported fatigue. Participants were randomly assigned to one of three treatment regimens:

  • Active tablets with high-dose soy lecithin (1200 mg per day)
  • Active tablets with low-dose soy lecithin (600 mg per day)
  • Placebo tablets

Women's data was collected before and after the study, including their age, menopause status, lifestyle habits, experienced menopause symptoms, and others. Fatigue and mood states were evaluated with a variety of assessment tools, such as the Profile of Mood States (POMS).

Study Findings

Women in the high-dose soy lecithin group showed significant improvements in the POMS score, diastolic blood pressure, and cardio-ankle vascular index. 

Researchers did not observe other statistically important improvements. No side effects were reported during the trial.

What Does It Mean?

As can be seen in the results of this clinical trial, high-dose soy lecithin improves fatigue in middle-aged women. It also exerts beneficial effects on diastolic blood pressure and cardio-ankle vascular index.

By doing so, soy lecithin can lower the risk of heart disease, such as high blood pressure, dyslipidemia, and diabetes. This is important as studies have shown that women are at a higher risk of cardiovascular disease.1

Vigor-increasing effects of soy lecithin can benefit menopausal women in numerous ways. Most importantly, it will allow them to choose natural solutions for their symptoms and restore their energy levels so that they can live up to their potential throughout the menopausal transition

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